Avobenzone

Avobenzone is oil soluble, effective UVA absorber. Adequate solubility in the formulation must be ensured in order to avoid recrystallization during storage. To maximize utilization and high performance, Avobenzone should be properly photo-stabilized. Excellent material for stabilizations is OCT. Other additional options would be 3-(4-Methylbenzyliden) Camphor or BP-3; Use a chelating agent like EDTA.

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CAS NO.: 70356-09-1
Chemical Formula: C20H22O3
Molecular Weight:310.39
EINECS NO.: 274-581-6
Assay: 99.0% min.

No Test items Specification
1 Appearance White to pale yellow powder
2 Identity (IR) USP<197K> Matches reference spectrum
 

3

Identity (Retention time) USP<621> Matches reference

retention time

 

4

UV specific extinction:

(E 1%,1 cm at 357 nm in ethanol)

Spectrophotometry USP<197U>

1100-1180
5 Melting point USP<741> 81.0℃~86.0℃
6 Loss on drying(%) USP<731) 0.5 max
 

7

Chromatographic

purity

GC USP<621>

Each impurity (%) 3.0 max
Total impurities(%) 4.5 max
8 Assay(%)GC USP<621> 95.0~105.0
9 Residual solvents GC USP<467> Methanol (ppm) 3000  max
Toluene (ppm) 890  max
 

 

10

Microbial purity Total amount of aerobe 100 CFU/g max
Total yeast and moulds 100 CFU/g max

Avobenzone Incompatibilities:
Multivalent metal cations should be avoided as they may form discolo-rations (E.g. Fe) or crystals due to lower solubility of the complexes (e.g.Al and Mg). Al coated Titanium Dioxides may lead to crystals. The combination of AVB and Zinc Oxide can interact to form a complex which may precipitate out. AVB is incompatible with formaldehyde donators which are mainly used as preservatives.

Avobenzone Regulatory status max concentration:
ASEAN 5%, China 5%, Europe 5%,Japan 10%, South Africa 5%,USA3%

Packaging: 20kg/Carton or 25kg/Carton

Shelf Life: 3 years